Pretibial myxedema
Pretibial myxedema is a localized lesions of the skin resulting from the deposition of
- [A] Fluid
- [B] Hyaluronic acid
- [C] beta-2 microglobulin
- [D] Transthyretin
All of the following are TRUE for Pretibial myxedema EXCEPT
- [A] almost always preceded by the ocular signs found in Graves’ disease
- [B] peau d’orange (orange peel) appearance
- [C] non-pitting edema of the skin
- [D] biopsy of the affected skin commonly reveals increase in fibroblasts
Pretibial myxedema
- Nearly always associated with autoimmune thyroid disease – Graves Disease
- Most often confined to the pretibial area, it may occur anywhere on the skin, especially the ankle, dorsum of the foot, knees, shoulders, elbows, upper back, pinnae, nose, and neck
